Dementia and Alzheimer’s Disease – Latest Report on Alzheimer’s Disease

Dementia is an age-associated condition, causing a reduction in mental or intellectual functioning.  The most common cause of dementia is Alzheimer’s disease. It accounts for 60 to 80% of all irreversible dementias, and is characterized chiefly by difficulty remembering names and recent events, and, very often, apathy and depression in the early stages. Later stages are marked with reduced judgment and reasoning, confusion and disorientation, behavior difficulties, and communication.

This month, the Alzheimer’s Association released its latest report on this disease, 2010 Alzheimer’s Disease Facts and Figures, the latest collection of statistics on its prevalence in different racial and ethnic groups, costs of care, and mortality. The full document can be found and downloaded from Alzheimer's report.

Some of the major highlights of this report include:

• Alzheimer’s disease was the 7th leading cause of death in the U.S. for 2006, across all ages, and the 5th leading cause of death for those over age 65. Deaths from this disease increased approximately 46% from 2000 thru 2006, in contrast with reductions in other diseases (stroke, down 18%, prostate cancer, down 8%, heart disease, down 11%, and HIV, down 16%).
• African-Americans and Hispanics are at greater risk than Caucasians, with the former group being about twice as likely, and the latter group being 1.5 times as likely as Caucasians to develop the condition. Though there is no known genetic factor that would account for these racial differences, other conditions, such as high blood pressure and diabetes are being studied as increased risk factors.
• Another significant finding is that African-Americans and Hispanics are less likely to be given the diagnosis, even though the rate of the disease is higher, reflecting that diagnoses will occur later in the course of the disease than for Caucasians.
• More women than men have dementia, because women live longer, and not due to any gender differences.
• Almost 11 million people in the U.S. provide care for a person with Alzheimer’s disease or related dementia.

The full report and other valuable information can be found on the website of the Alzheimer’s Association.

The CoHealth website endeavors to provide helpful educational programs for all caregivers working with older adults, from professionals, to home care providers, to family members. See the entire range of educational programs at http://www.cohealth.org/. Two especially useful programs are the CoHealth courses on differentiating among depression, dementia, and delirium, and understanding sensory losses that occur with aging. Continuing education credit is available for many health care disciplines.

Understanding Dementia – Clinical Signs and Symptoms

Caregivers who work with older adults with dementia can benefit from understanding what toll the disease takes on a patient’s functioning. Earlier blogs have described many of the cognitive, behavioral and emotional changes that accompanying this dementing process. Today’s blog outlines the specific changes in mental ability that occurs, including the clinical signs of the disease.

Dementia is a syndrome or collection of symptoms that result in a global, or diffuse deterioration of intellectual abilities. It is important to recognize that the term dementia, in and of itself, does not say anything about the cause, or whether it is reversible. Of course, we are most familiar with primary degenerative dementias, which are caused by specific disease processes, such as Alzheimer’s disease, vascular conditions, Parkinson’s disease, and many others.

However, there are also secondary, or reversible (i.e., treatable) causes of dementia, including medications and dietary factors that can produce the same losses in intellectual functioning that we may see with a primary degenerative dementia. Pseudo-dementia (or false dementia) is the term for the dementia-like condition that is caused by severe depression. These treatable dementias are more common in community-dwelling elderly, especially those living alone, than in long term care settings, where treatable conditions have generally been ruled out.

One of the hallmarks of dementia is a loss of memory, especially memory for recent events (such as where an individual parked her car, or what she had for breakfast). More remote, or long term memory is generally intact. There is a loss of comprehension ability, which over time, limits how much the person understands what is being communicated. There is a loss of general information, that is, everyday facts and details that are commonly known by unimpaired individuals, such as the season, or major local or world events. We often see changes in attention and concentration ability, limiting the ability to stay on task for more than a few minutes. Judgment and common sense gradually decline with this condition, as do executive functions, such as reasoning ability and decision making.

There is a gradual loss of orientation, or what is also referred to as changes in sensorium. Cognitively-intact individuals are generally oriented in the temporal sphere (i.e., time), spatial sphere (i.e., place), and personal sphere (i.e., person). However, dementia results in a gradual loss of this orientation, first in the temporal, then spatial, and finally in the personal sphere. The remaining major cognitive changes we see in dementia are those related to verbal and language skills, first seen in word-finding difficulty and the ability to put ideas, thoughts, and needs into words. This progresses over time to severe deficits in the ability to communicate.

These changes occur insidiously, or cumulatively over time, and do not follow the same exact course for each individual affected. This makes it hard for caregivers to know what to expect, and how to adapt to the new losses in functioning. However, as we better understand these changes, and learn approaches that make up for or re-supply what is missing, there are fewer altercations and power struggles, and more time to focus on the individual’s residual strengths and capacities. These caregiving approaches will be discussed in coming weeks.

For more insights into these issues, see the CoHealth online programs on differentiating among depression, dementia, and delirium and on managing problem behaviors in dementia patients.  Useful, informative programs for families on facing Alzheimer's disease is also available on our website.  Visit the CoHealth website for more details about us, or mission, and our programs.